Pharmacological category: vitamin supplement, coenzyme activator, metabolic regulator, skin/hair/nail health fortifier
1.Mechanism of action:
Biotin (Vitamin B7/H) is an essential water-soluble vitamin, core function is to act as a coenzyme for carboxylase enzymes, participating in fatty acid synthesis, amino acid catabolism, gluconeogenesis and macronutrient metabolism, promoting energy-yielding reactions, improving energy metabolism efficiency. It supports epidermal cell growth/differentiation, enhances keratin structure of hair roots and nail matrix, improves hair follicle and nail bed nutrition supply, prevents hair loss and brittle nails; water-soluble, no body storage, oral absorption fast, capsule form avoids taste irritation, high compliance and bioavailability, no liver and kidney burden, high safety and biocompatibility.
2.Indications:
·Prevention and treatment of biotin deficiency caused by malnutrition, rapid weight loss, long-term tube feeding, chronic intestinal disease, alcoholism.
·Hair health: Adjuvant improvement of hair loss, thinning hair, dryness, splitting caused by biotin deficiency, suitable for postpartum hair loss, stress hair loss, aging-related hair loss.
·Nail health: Relief of brittle, splitting, soft nails, improvement of nail strength and gloss, applicable to nail damage, nail growth retardation groups.
·Skin health: Adjuvant treatment of seborrheic dermatitis, eczema, dry skin, promotion of skin barrier repair and renewal.
·Metabolic support: Nutritional supplement for diabetes, hyperlipidemia, fatty liver to assist macronutrient metabolism, improve energy metabolism efficiency.
·General nutrition: Daily supplement for vegetarians, vegans, elderly, pregnant/lactating women to maintain normal metabolism and physiological function.
3.Usage and dosage:
Oral administration, take with warm water with meals to promote absorption, no food restriction.
·Adult regular dose: 500mcg-1000mcg (1-2 capsules) once a day, or 5000mcg (1 capsule) once a day.
·Hair/nail intensive care: 5000mcg-10,000mcg (1 capsule) once a day, 3-6 months as a cycle, follow healthcare professional guidance.
·Deficiency correction: 1000mcg-5000mcg (1-5 capsules) daily, adjust according to deficiency level, under medical supervision.
·Children over 6 years old: 500mcg (1 capsule) once a day, adjust by weight, consult pediatrician first.
4.Contraindications:
Hypersensitivity to biotin, capsule excipients (vegetable cellulose, gelatin) or any raw materials of the product.
5.Cautious population:
·Pregnant and lactating women: Standard dose is safe, meet maternal and fetal nutritional needs, consult doctor before high-dose use.
·Severe renal insufficiency patients: Use cautiously, monitor renal function regularly, adjust dosage appropriately.
·Patients taking antiepileptic drugs, antibiotics, isotretinoin: May reduce biotin absorption, separate taking time by 2-3 hours.
·High-dose users (>2500mcg/day): May interfere with immunoassay lab tests (e.g., thyroid function, troponin), inform doctor/pharmacist before testing.
·Allergic constitution: Monitor mild rash, pruritus, stop medication if discomfort occurs.
6.Adverse reactions:
Ultra-high safety, mild and rare adverse reactions, excellent tolerance, no severe toxic and side effects.
·Common reactions (<1%): Occasional mild gastrointestinal discomfort (nausea, abdominal distension, loose stool), relieved spontaneously after taking with meals or reducing dosage.
·Rare reactions (<0.1%): Mild allergic reactions (skin rash, pruritus); high-dose intake may cause acne, adjust dosage to relieve.
·No hepatotoxicity, nephrotoxicity, drug dependence or withdrawal reaction, safe for long-term low-dose supplementation.
7.Notes:
·Do not exceed recommended dosage; high-dose use (>10,000mcg/day) must be under healthcare professional guidance.
·Capsule is hard/soft gel with white/off-white powder/liquid inside; forbidden to use if capsule is cracked, content is discolored, damp or agglomerated.
·High-dose biotin may interfere with lab tests, inform medical staff of supplementation before testing.
·Storage: Cool and dry place, sealed, protected from light and moisture, room temperature ≤25℃.
·Validity period: 24-36 months (varies by manufacturer).
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