500mg Metamizole Sodium Injection (Analgin Injection)

Indications: Relief of moderate to severe pain (headache, toothache, neuralgia, muscle pain, joint pain, dysmenorrhea, postoperative pain); emergency treatment of high fever and hyperpyrexia that is ineffective to other antipyretics; adjuvant treatment of inflammatory pain caused by rheumatoid arthritis and soft tissue inflammation.

Usage and dosage: Intramuscular injection / slow intravenous injection. Adult: 0.5g ~ 1.0g (1~2 ampoules) once a time, 1~2 times a day, the maximum daily dose ≤ 2.0g. Pediatric: 5~10mg per kg body weight per time, once a day, strictly follow the doctor's advice for dosage adjustment.

Contraindications: Contraindicated in patients allergic to this product, pyrazolone derivatives and any excipients; contraindicated in patients with severe granulocytopenia and agranulocytosis; contraindicated in patients with severe hepatic and renal insufficiency and severe heart failure; contraindicated in pregnant women, lactating women and infants under 3 months old.

Cautious population: Use with extreme caution in patients with a history of blood system diseases; use with caution in elderly patients with reduced organ function (reduce dosage); use with caution in patients with gastric ulcer and gastrointestinal bleeding history; long-term use should monitor blood routine regularly to avoid bone marrow suppression; avoid combined use with other analgesics and antipyretics to prevent overdose.

Adverse reactions: Common reactions: mild local pain, swelling and induration at intramuscular injection site; occasional dizziness, headache, fatigue, nausea and mild gastrointestinal discomfort. Rare adverse reactions: allergic reactions (skin rash, pruritus, urticaria), severe anaphylactic shock (rare); long-term large-dose use may cause granulocytopenia, thrombocytopenia and other blood system abnormalities (reversible after drug withdrawal). Note: The incidence of adverse reactions is low with conventional dosage, high safety for short-term use.

Notes: Do not mix with other drugs in the same syringe/infusion bottle to avoid precipitation and drug interaction; slow intravenous injection is recommended to prevent hypotension and arrhythmia; stop medication immediately if rash, fever or other allergic symptoms occur; short-term use is recommended (no more than 3 days for fever, no more than 7 days for pain) to avoid long-term side effects; store in a cool and dark place, avoid light and high temperature.